In June 1952, the Institute of Medicine was established and Dr. Jesus B. Nolasco was appointed Secretary of the Institute and Head of the Department of Physiology and Biochemistry. Among the pioneer staff members of the department of Physiology and Biochemistry were: Drs. Alfredo Navato, Deogracias Rodil, Rodolfo Madlangsacay, Baltazar Solis, Gloria Roque, Felicisimo Guevara, Jose Tomas, Lucila Casabar, Romeo Marfa, Tomas Nazario and Benjamin Razon. The Institute of Medicine pioneered in innovations in the field of medical education, the course in Physiology and Biochemistry became year-long subjects in order that the teaching of Anatomy can be coordinated with the teaching of Biochemistry and Physiology.
|Joel Javate, M.D.|
|Romulo de Villa, M.D.|
|Jose R. Tomas, M.D.|
|Alfredo Navato, M.D.|
|Jesus B. Nolasco, M.D.|
Dr. Remedios P. Santos
Dr. Rebecca A. Villanueva
Dr. Joel Javate
Dr. Anna Belen I. Alensuela
Dr. Mari-Ann B. Bringas
Dr. Dennis Bravo
Dr. Hena Alcantara
Dr. May Gabaldon
Medical Biochemistry (First Year Subject)
The focus of biochemistry is metabolism involving protein enzymes while the focus of molecular biology is the encoding of proteins into a simple macromolecule with a simple mechanism of replication or self propagation and a simple mechanism of maintaining fidelity of replication. The processes in molecular biology such as replication, transcription and translation utilize protein enzymes. Thus, intimately linking biochemistry and molecular biology. Organic chemistry explains the molecular events that take place on the substances processed by protein enzymes. These molecular events also occur on the protein enzymes themselves. Again intimately linking biochemistry and organic chemistry.
All diseases of man can be explained at molecular level particularly to a structural alteration of a biomolecule. This is the reason why biochemistry can be considered as a foundation of all other subjects in medicine including anatomy, physiology, pharmacology, pathology, laboratory diagnosis, medicine, pediatrics, surgery, obstetrics and gynecology, anesthesiology, and radiology.
The topics covered in medical biochemistry are: structure, function and metabolism of proteins, carbohydrates, lipids, and nucleic acids; enzymology; bioenergetics/biologic oxidation; metabolic control; DNA replication/ gene expression; nutrition (including vitamins & minerals); special tissues; acid/base, water, electrolytes; chemistry of respiration; blood and immunology; and molecular biology.
The teaching methods used are:
- Laboratory experiments
- Clinical conferences
- Scientific poster presentation & scientific journal reporting.
- Basic principles are given during the lecture/discussion
- Laboratory experiments illustrate the basic principles of quantification and detection of substances found in the body fluids
- Clinical conferences illustrate the connection of biochemistry with physiology, anatomy and clinical subjects such as medicine, pediatrics’, surgery, obstetrics and gynecology.
- Journal reporting and poster presentation teaches the students to evaluate new information given in published journal articles.
Applied Nutrition (Third year subject)
This course gives emphasis on the role of nutrition as the key to good health. It includes a consideration of the importance of nutrition in health and in diseases, what food to eat and not to eat, physiopathology and causes of acute and chronic malnutrition, of deficiency diseases, functions of vitamins, minerals, trace elements, fiber, phytonutrients, probiotics and test for deficiency chronic and acute, principles of dietetics and diet calculation. This course teaches the students about nutritional therapy/diet prescription which has same importance as the drug prescription in medicine. It designates the type, amount, frequency, and route and food ingestion just as the drug prescription identifies the drug name, dosage, frequency and route of administration. The diet prescription includes the daily caloric requirements based on the individual’s desirable body weight and normal activity plus the amounts and forms of needed protein, fat and carbohydrate, minerals, vitamins and other substances such as
fiber and fluids.
Basic principles are given during the Lecture/Discussion. Clinical conferences and small group discussions will emphasize the dietary management of different clinical conditions. This subject will also include discussion of enteral and parenteral nutrition for critically-ill patients.
Awarded 4th place in the annual assessment using 5S. (2014)